Key Concerns in Microbial Biologic Development
Undaunted by the many challenges posed by biologics processing, developers continue seeking out new techniques. Biopharmaceuticals (or biologics), while not exactly a new technology, are a fascinating and lucrative medical frontier to explore. The first [...]
Current Techniques in Monoclonal Antibody Development
As the complexity of mAbs continues to grow, developers explore the potential of new techniques and expression systems. The development of mAbs (monoclonal antibodies) has come a long way since 1986, when the first mAb, [...]
Solid Oral Dosage Vaccine Development and Manufacturing
Challenges of adapting vaccines for oral administration remain significant, but emerging techniques promise greater flexibility and efficiency. Pressures to streamline development and production continue to ramp up in many areas of the pharmaceutical industry. This [...]
Emerging Trends in Sterile Fill and Finish Technology
New packaging materials, disposable devices and automated systems offer enhanced performance. The core goals of an aseptic fill and finish process have remained essentially the same for more than two decades. Manufacturers of sterile drugs [...]
Prefilled Syringe Manufacturing for Biopharmaceuticals
Regulations in this sector are rapidly tightening, but advances in materials and manufacturing techniques can help manufacturers meet rising expectations. As biopharmaceutical formulations capture ever-greater market share, demand for self-administered delivery systems has fueled rapid [...]
3 Challenging Complexities of Preclinical Toxicology Studies
Before a drug can proceed to the clinical trial stage, its developer must first pinpoint its likelihood of harming people by performing in vitro and in vivo toxicological studies. These studies involve a number [...]